Article
Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy.
The Journal of cell biology - 23 Jun 2003
Herrmann Thomas, van der Hoeven Frank, Grone Hermann-Josef, Stewart Adrian Francis, Langbein Lutz, Kaiser Iris, Liebisch Gerhard, Gosch Isabella, Buchkremer Florian, Drobnik Wolfgang, Schmitz Gerd, Stremmel Wolfgang
Abstract excerpt
The fatty acid transport protein family is a group of evolutionarily conserved proteins that are involved in the cellular uptake and metabolism of long and very long chain fatty acids. However, little is known about their respective physiological roles. To analyze the functional significance of fatty acid transport protein 4 (Fatp4, Slc27a4), we generated mice with a targeted disruption of the Fatp4 gene....
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