Killer Cell Immunoglobulin-like Receptors Influence the Innate and Adaptive Immune Responses.

Abstract excerpt

Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon- (IFN-) and tumor necrosis factor (TNF) prompting adaptive immunity. NK cells distinguish the unhealthy cells from the healthy ones through an array of cell-surface receptors. Human NK cells use inhibitory and activating...

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