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Article

Noradrenaline is necessary for the hedonic properties of addictive drugs.

Vascular pharmacology - 1 Oct 2006

Jasmin Luc, Narasaiah Mena, Tien Duc

Abstract excerpt

To determine whether noradrenaline (NA) is an essential neurotransmitter for addictive and appetitive behaviors, we measured drug and food seeking in transgenic mice lacking dopamine beta-hydroxylase (Dbh), the enzyme responsible for synthesizing NA. Using the conditioned place preference test (CPP), we show that Dbh -/- mice do not exhibit rewarding behavior to morphine, cocaine, or the mixed reuptake inhibitor...

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Source

Identifiers

PMID: 16899413
DOI: 10.1016/j.vph.2005.08.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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