Article
The Role of Mesolimbic Reward Neurocircuitry in Prevention and Rescue of the Activity-Based Anorexia (ABA) Phenotype in Rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2017
Foldi Claire J, Milton Laura K, Oldfield Brian J
Abstract excerpt
Patients suffering from anorexia nervosa (AN) become anhedonic; unable or unwilling to derive normal pleasures and avoid rewarding outcomes, most profoundly in food intake. The activity-based anorexia (ABA) model recapitulates many of the characteristics of the human condition, including anhedonia, and allows investigation of the underlying neurobiology of AN. The potential for increased neuronal activity in...
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