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Article

C957T polymorphism of the dopamine D2 receptor gene modulates the effect of nicotine on working memory performance and cortical processing efficiency.

Psychopharmacology - 1 Nov 2006

Jacobsen Leslie K, Pugh Kenneth R, Mencl W Einar, Gelernter Joel

Abstract excerpt

RATIONALE: In both animals and humans, nicotine produces behavioral effects that vary across individuals. Studies examining the role of genetic variability in modulating individual response to nicotine in humans have increased, with recent work showing that genetic variation at the dopamine D2 receptor (DRD2) predicts response to pharmacotherapy for tobacco dependence. OBJECTIVES: To determine whether a...

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Source

Identifiers

PMID: 16896957
DOI: 10.1007/s00213-006-0469-1

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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