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Article

Modulation of nicotine effects on selective attention by DRD2 and CHRNA4 gene polymorphisms.

Psychopharmacology - 1 Jul 2015

Ahrens Stefan, Markett Sebastian, Breckel Thomas P K, Behler Oliver, Reuter Martin, Thiel Christiane M

Abstract excerpt

RATIONALE: Pharmacological and genetic modulation of cholinergic nicotinic neurotransmission influence visuospatial attention in humans. Prior studies show that nicotine as well as a single nucleotide polymorphism (SNP) in the gene coding for the alpha 4 subunit of the nicotinic acetylcholine receptor (CHRNA4) modulate visuospatial attention and distractor interference. The CHRNA4 gene synergistically interacts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25647695
DOI: 10.1007/s00213-015-3869-2

Genes

CHRNA4
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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