Article
Complement dysfunction in hemolytic uremic syndrome.
Current opinion in rheumatology - 1 Sept 2006
Zipfel Peter F, Skerka Christine
Abstract excerpt
PURPOSE OF REVIEW: Hemolytic uremic syndrome is a rare disease of microangiopathic hemolytic anemia, low platelet count and is associated with renal impairment. The atypical form, which occurs in adult patients, is associated with defective complement control. RECENT FINDINGS: Recent data show that atypical hemolytic uremic syndrome is a genetic disease and gene mutations have been reported for factor H, membrane...
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