Article
Update on evaluating complement in hemolytic uremic syndrome.
Current opinion in nephrology and hypertension - 1 Nov 2007
Kavanagh David, Goodship Timothy H
Abstract excerpt
PURPOSE OF REVIEW: The last few years have seen the decoding of the genetic basis for atypical hemolytic uremic syndrome. RECENT FINDINGS: Mutations in complement factor H were the first to be associated with atypical hemolytic uremic syndrome. These mutations cluster in the C-terminus of complement factor H. This year has seen the publication of a transgenic mouse model lacking the C-terminus of complement...
Topics
Join the communities discussing this publication.
