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Article

Antagonism between two mechanisms of antifungal drug resistance.

Eukaryotic cell - 1 Aug 2006

Anderson James B, Ricker Nicole, Sirjusingh Caroline

Abstract excerpt

This study tested for interaction between two independently evolved mechanisms of fluconazole resistance in Saccharomyces cerevisiae. One set of strains was from a 400-generation evolution experiment, during which the concentration of fluconazole was increased from 16 to 256 microg/ml in four increments. At 100 generations, populations became fixed for resistance mutations in either of two transcriptional...

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Identifiers

PMID: 16896209
DOI: 10.1128/EC.00048-06
PMCID: PMC1539145

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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