Article
yEvo: experimental evolution in high school classrooms selects for novel mutations that impact clotrimazole resistance in Saccharomyces cerevisiae.
G3 (Bethesda, Md.) - 4 Nov 2022
Taylor Matthew Bryce, Skophammer Ryan, Warwick Alexa R, Geck Renee C, Boyer Josephine M, Walson Margaux, Large Christopher R L, Hickey Angela Shang-Mei, Rowley Paul A, Dunham Maitreya J
Abstract excerpt
Antifungal resistance in pathogenic fungi is a growing global health concern. Nonpathogenic laboratory strains of Saccharomyces cerevisiae are an important model for studying mechanisms of antifungal resistance that are relevant to understanding the same processes in pathogenic fungi. We have developed a series of laboratory modules in which high school students used experimental evolution to study antifungal...
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