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Article

Haploidy, diploidy and evolution of antifungal drug resistance in Saccharomyces cerevisiae.

Genetics - 1 Dec 2004

Anderson James B, Sirjusingh Caroline, Ricker Nicole

Abstract excerpt

We tested the hypothesis that the time course of the evolution of antifungal drug resistance depends on the ploidy of the fungus. The experiments were designed to measure the initial response to the selection imposed by the antifungal drug fluconazole up to and including the fixation of the first resistance mutation in populations of Saccharomyces cerevisiae. Under conditions of low drug concentration, mutations...

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Identifiers

PMID: 15371350
DOI: 10.1534/genetics.104.033266
PMCID: PMC1448728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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