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Article

The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.

Nucleic acids research - 1 Jan 2006

Shikazono Naoya, Pearson Colin, O'Neill Peter, Thacker John

Abstract excerpt

The potential for genetic change arising from specific single types of DNA lesion has been thoroughly explored, but much less is known about the mutagenic effects of DNA lesions present in clustered damage sites. Localized clustering of damage is a hallmark of certain DNA-damaging agents, particularly ionizing radiation. We have investigated the potential of a non-mutagenic DNA base lesion, 5,6-dihydrothymine...

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Identifiers

PMID: 16893955
DOI: 10.1093/nar/gkl503
PMCID: PMC1557791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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