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Article

Delayed repair of radiation induced clustered DNA damage: Friend or foe?

3 Dec 2010

Abstract excerpt

A signature of ionizing radiation exposure is the induction of DNA clustered damaged sites, defined as two or more lesions within one to two helical turns of DNA by passage of a single radiation track. Clustered damage is made up of double strand breaks (DSB) with associated base lesions or abasic (AP) sites, and non-DSB clusters comprised of base lesions, AP sites and single strand breaks. This review will...

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PMID: 21130102
DOI: 10.1016/j.mrfmmm.2010.11.003

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