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Article

Brain-derived neurotrophic factor Val66Met polymorphism and dexamethasone/CRH test results in depressed patients.

Psychoneuroendocrinology - 1 Sept 2006

Schüle Cornelius, Zill Peter, Baghai Thomas C, Eser Daniela, Zwanzger Peter, Wenig Nadine, Rupprecht Rainer, Bondy Brigitta

Abstract excerpt

Data suggest that both neurotrophic and hypothalamic-pituitary-adrenocortical (HPA) systems are involved in the pathophysiology of depression. The aim of the present study was to investigate whether the non-conservative brain-derived neurotrophic factor (BDNF) Val66Met polymorphism has an impact on HPA axis activity in depressed patients. At admission, the dexamethasone/CRH (DEX/CRH) test was performed in 187...

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Source

Identifiers

PMID: 16890377
DOI: 10.1016/j.psyneuen.2006.06.002

Genes

CRH
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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