Article
The BDNF Val66Met polymorphism: relation to familiar risk of affective disorder, BDNF levels and salivary cortisol.
Psychoneuroendocrinology - 1 Oct 2009
Vinberg Maj, Trajkovska Viktorija, Bennike Bente, Knorr Ulla, Knudsen Gitte M, Kessing Lars V
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) and the hypothalamic-pituitary-adrenal (HPA) axis are considered to play an important role in the pathophysiology of affective disorders. The aim of the present study was to investigate whether the BDNF Val66Met polymorphism is associated with a familiar risk of affective disorder and whether these genotypes affect whole blood BDNF level and salivary cortisol....
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