Article
The BDNF Val66Met polymorphism affects HPA-axis reactivity to acute stress.
Psychoneuroendocrinology - 1 Jul 2010
Alexander Nina, Osinsky Roman, Schmitz Anja, Mueller Eva, Kuepper Yvonne, Hennig Juergen
Abstract excerpt
BACKGROUND: Growing evidence suggests that individual differences in HPA-axis reactivity to psychosocial stress are partly due to heritable influences. However, knowledge about the role of specific genetic variants remains very limited to date. Since brain-derived neurotrophic factor (BDNF) not only exhibits neurotrophic actions but is also involved in the regulation of hypothalamic neuropeptides, we investigated...
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