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Article

Mitotic activation of the kinase Aurora-A requires its binding partner Bora.

Developmental cell - 1 Aug 2006

Hutterer Andrea, Berdnik Daniela, Wirtz-Peitz Frederik, Zigman Mihaela, Schleiffer Alexander, Knoblich Juergen A

Abstract excerpt

The protein kinase Aurora-A is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis. Here, we describe the identification of Bora, a conserved protein that is required for the activation of Aurora-A at the onset of mitosis. In the Drosophila peripheral nervous system, bora mutants have defects during asymmetric cell division identical to those observed in...

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Identifiers

PMID: 16890155
DOI: 10.1016/j.devcel.2006.06.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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