Article
Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
Developmental cell - 1 Aug 2006
Hutterer Andrea, Berdnik Daniela, Wirtz-Peitz Frederik, Zigman Mihaela, Schleiffer Alexander, Knoblich Juergen A
Abstract excerpt
The protein kinase Aurora-A is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis. Here, we describe the identification of Bora, a conserved protein that is required for the activation of Aurora-A at the onset of mitosis. In the Drosophila per...
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