Article
Pathogenesis of allergic airway inflammation.
Current allergy and asthma reports - 1 Jan 2010
Agrawal Devendra K, Shao Zhifei
Abstract excerpt
Advances have been made in defining the mechanisms for the control of allergic airway inflammation in response to inhaled antigens. Several genes, including ADAM33, DPP10, PHF11, GPRA, TIM-1, PDE4D, OPN3, and ORMDL3, have been implicated in the pathogenesis and susceptibility to atopy and asthma. Growing evidence associates asthma with a systemic propensity for allergic T-helper type 2 cytokines. Disordered...
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