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Article

Complement fragments C3a and C5a: The salt and pepper of the immune response

22 Feb 2010

Abstract excerpt

The influence of complement on B-cell responses has been known for many years, but the notion that T-cell recognition, expansion and differentiation are complement dependent has only recently gained impetus. DC, and to a lesser extent T cells, produce a range of complement components necessary for complement activation, and these cells also express receptors that detect complement-activation products such as C3a...

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PMID: 20186746
DOI: 10.1002/eji.201040355

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