Article
A complex role for complement in allergic asthma.
Expert review of clinical immunology - 1 Mar 2010
Zhang Xun, Köhl Jörg
Abstract excerpt
Allergic asthma is a chronic inflammatory disease of the upper airway. It is well appreciated that maladaptive Th2 immunity promotes the allergic phenotype, the underlying mechanisms of which remain elusive. The disease is associated with activation of complement, an ancient danger-sensing component of the innate immune system. Different models of experimental allergic asthma suggest that the small complement...
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