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Article

Complement’s involvement in allergic Th2 immunity: a cross-barrier perspective

1 May 2025

Abstract excerpt

Type 2 (Th2) allergic diseases are chronic conditions characterized by a Th2-polarized immune response to allergens. These diseases can be categorized by affected barrier sites: skin (atopic dermatitis, allergic contact dermatitis), gut (food allergy), and respiratory tract (e.g., asthma, chronic rhinosinusitis). The global prevalence of Th2 allergic diseases has increased the need for a deeper understanding of...

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PMID: 40309766
DOI: 10.1172/jci188352

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