Article
Mutations affecting primer RNA interaction with the replication repressor RNA I in plasmid CoIE1: potential RNA folding pathway mutants.
The EMBO journal - 1 Jan 1990
Polisky B, Zhang X Y, Fitzwater T
Abstract excerpt
The control of plasmid ColE1 copy number is mediated by the kinetics of interaction of two complementary plasmid-encoded RNAs. One RNA is the primer precursor and the other is a small counter-transcript called RNA I. The interaction of these highly structured RNAs results in inhibition of formati...
Topics
- Base Sequence
- Biological Evolution
- DNA-Directed RNA Polymerases
- Escherichia coli
- Kinetics
- Models, Biological
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Plasmids
- RNA
- RNA, Bacterial
- Transcription, Genetic
