Antisense-RNA mediated transcriptional attenuation: importance of a U-turn loop structure in the target RNA of plasmid pIP501 for efficient inhibition by the antisense RNA.

Abstract excerpt

Antisense-RNA mediated gene regulation has been found and studied in detail mainly in prokaryotic accessory DNA elements. In spite of different regulatory mechanisms, in all cases a rapid interaction between antisense and target RNA has been shown to be crucial for efficient regulation. Recently, a sequence comparison revealed in 45 antisense RNA control systems a 5' YUNR motif indicative for the formation of a...

Topics

• Bacillus subtilis
• Base Sequence
• Ethylnitrosourea
• Kinetics
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• Plasmids
• RNA, Antisense
• Transcription, Genetic