Article
When pol I goes into high gear: processive DNA synthesis by pol I in the cell.
Cell cycle (Georgetown, Tex.) - 1 Feb 2004
Camps Manel, Loeb Lawrence A
Abstract excerpt
Pol I is the most abundant polymerase in E. coli and plays an important role in short patch repair. In accord with this role in the cell, the purified polymerase exhibits low processivity and high fidelity in vitro. Pol I is also the polymerase responsible for leader strand synthesis during ColE1 plasmid replication. In a previous publication, we described the generation of a highly error-prone DNA polymerase I....
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