Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gynecological tumors revealing hereditary nonpolyposis colorectal cancer: analysis of a large Lebanese pedigree.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000

Akoum R, Ghaoui A, Brihi E, Ghabash M, Abou Atme J

Abstract excerpt

The objective of this study was to evaluate the aggregation of colorectal cancer (CRC) and hereditary nonpolyposis colorectal cancer (HNPCC)-related extracolonic cancers in an extended Lebanese family with HNPCC. This was a pedigree analysis and a prospective follow-up over an 8-year period. The causative germ line mutation was detected using denaturing high-performance liquid chromatography, polymerase chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Papillary
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to Endometrial Neoplasms

Share to Germ-Line Mutation

Share to Lebanon

Share to MutS Homolog 2 Protein

Share to Population Surveillance

Source

Identifiers

PMID: 16884359
DOI: 10.1111/j.1525-1438.2006.00621.x

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gynecological tumors revealing hereditary nonpolyposis colorectal cancer: analysis of a large Lebanese pedigree.PMID 16884359Read ↗

Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.Semantic proximity Read ↗

Clinical and molecular diagnosis of hereditary non-polyposis colorectal cancer: problems and pitfalls in an extended pedigree.Semantic proximity Read ↗

Hereditary nonpolyposis colorectal cancer identification and surveillance of high-risk families.Semantic proximity Read ↗

Clinical and genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer families.Semantic proximity Read ↗

Gynecologic manifestations of hereditary nonpolyposis colorectal cancer. From inherited to sporadic disease.Semantic proximity Read ↗

Association of colonic and endometrial carcinomas in Portuguese families with hereditary nonpolyposis colorectal carcinoma significantly increases the probability of detecting a pathogenic mutation in mismatch repair genes, primarily the MSH2 gene.Semantic proximity Read ↗

Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.Semantic proximity Read ↗

Hereditary non-polyposis colorectal cancer: clinical and molecular evidence for a new entity of hereditary colorectal cancer.Semantic proximity Read ↗

Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians.Semantic proximity Read ↗

Hereditary non-polyposis colorectal cancer (HNPCC): phenotype-genotype correlation between patients with and without identified mutation.Semantic proximity Read ↗

Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family study.Semantic proximity Read ↗

Hereditary nonpolyposis colorectal cancer with gynecologic malignancies: report of two families in Taiwan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.