Article
The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman.
Proceedings of the National Academy of Sciences of the United States of America - 8 Aug 2006
Akasaka Takeshi, Klinedinst Susan, Ocorr Karen, Bustamante Erika L, Kim Seung K, Bodmer Rolf
Abstract excerpt
The homeobox transcription factor Tinman plays an important role in the initiation of heart development. Later functions of Tinman, including the target genes involved in cardiac physiology, are less well studied. We focused on the dSUR gene, which encodes an ATP-binding cassette transmembrane protein that is expressed in the heart. Mammalian SUR genes are associated with K(ATP) (ATP-sensitive potassium)...
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