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Article

Transcription factor neuromancer/TBX20 is required for cardiac function in <i>Drosophila</i> with implications for human heart disease

12 Dec 2008

Abstract excerpt

neuromancer/Tbx20 (nmr) genes are cardiac T-box transcription factors that are evolutionarily conserved from flies to humans. Along with other known congenital heart disease genes, including tinman/Nkx2-5, dorsocross/Tbx5/6, and pannier/Gata4/6, they are important for specification and morphogenesis of the embryonic heart. The Drosophila heart has proven to be an excellent model to study genes involved in...

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PMID: 19074289
DOI: 10.1073/pnas.0808705105

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Transcription factor neuromancer/TBX20 is required for cardiac function in <i>Drosophila</i> with implications for human heart diseasePMID 19074289Read ↗

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