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Article

A glutamic acid 3-methyltransferase encoded by an accessory gene locus important for daptomycin biosynthesis in Streptomyces roseosporus.

Molecular microbiology - 1 Sept 2006

Nguyen Kien T, Kau David, Gu Jian-Qiao, Brian Paul, Wrigley Stephen K, Baltz Richard H, Miao Vivian

Abstract excerpt

In many peptide antibiotics, modified amino acids are important for biological activity. The amino acid 3-methyl-glutamic acid (3mGlu) has been found only in three cyclic lipopeptide antibiotics: daptomycin and the A21978C family produced by Streptomyces roseosporus, calcium-dependent antibiotic...

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Identifiers

PMID: 16879412
DOI: 10.1111/j.1365-2958.2006.05305.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16879412-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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