Article
[Effects of afobazole on the BDNF content in brain structures of inbred mice with different phenotypes of emotional stress reaction].
Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2000
Seredin S B, Melkumian D S, Val'dman E A, Iarkova M A, Seredina T C, Voronin M V, Lapitskaia A S
Abstract excerpt
Changes in the BDNF content in brain structures--hippocampus, hypothalamus, striatum, and frontal cortex--were determined in mice of different emotional-stress reaction phenotypes, which were subjected to emotional stress and treated by the selective anxiolytic afobazole. The changes were different in BALB/c and C57BL/6 mice. Afobazole exhibited a significant protector action against a decrease in the brain BDNF...
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