Article
[The anxiolytic effect of the new 2-mercaptobenzimidazole derivative in MR and MNRA rats].
Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2000
Seredinin S B, Viglinskaia I V, Kolik L G
Abstract excerpt
The effect of the new drug SM-346, a derivative of 2-mercaptobenzimidazole, on the behavior of inbred MR and MNRA rats, differing in the phenotype of the emotional-stress reaction in the open field test was studies. In the Vogel conflict test SM-346 in a dose of 1 mg/kg produced an anxiolytic effect in MR rats but had no effect on the behavior of MNRA rats. The obtained results allow the conclusion that SM-346...
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