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Article

Chimeric Fc receptors identify ligand binding regions in human glycoprotein VI.

Journal of molecular biology - 1 Sept 2006

Dumont Bénédicte, Minullina Izida, Loyau Stéphane, Monteiro Renato C, Lacapere Jean-Jacques, Arocas Véronique, Jandrot-Perrus Martine

Abstract excerpt

Glycoprotein (GP) VI, a key receptor for collagen-induced platelet activation, recently emerged as a major target for developing new antithrombotics. However, little is known about its functional domains, which is a disadvantage for the rational development of antagonists. Our aim was to identify the structures determining GPVI specificity. GPVI presents homologies with members of the Ig superfamily (in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16876821
DOI: 10.1016/j.jmb.2006.06.053

Genes

CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Chimeric Fc receptors identify ligand binding regions in human glycoprotein VI.PMID 16876821Read ↗

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