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Article

A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder.

Journal of thrombosis and haemostasis : JTH - 1 Aug 2009

Hermans C, Wittevrongel C, Thys C, Smethurst P A, Van Geet C, Freson K

Abstract excerpt

BACKGROUND: The physiological relevance of the collagen glycoprotein VI (GPVI) receptor was known prior to its recognition as a platelet membrane receptor as several patients lacking GPVI as a consequence of autoantibody inhibition presented with a mild bleeding diathesis. Remarkably, patients with a proven GPVI gene mutation have not yet been identified. RESULTS: In the present study, we describe a patient with...

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PMID: 19552682
DOI: 10.1111/j.1538-7836.2009.03520.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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