Article
Transcriptional priming and chromatin regulation during stochastic cell fate specification.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 22 Apr 2024
Ordway Alison J, Helt Rina N, Johnston Robert J
Abstract excerpt
Stochastic cell fate specification, in which a cell chooses between two or more fates with a set probability, diversifies cell subtypes in development. Although this is a vital process across species, a common mechanism for these cell fate decisions remains elusive. This review examines two well-characterized stochastic cell fate decisions to identify commonalities between their developmental programmes. In the...
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