Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of L-lysine production in methylotroph Methylophilus methylotrophus by introducing a mutant LysE exporter.

Journal of biotechnology - 15 Dec 2006

Gunji Yoshiya, Yasueda Hisashi

Abstract excerpt

The obligate methylotroph Methylophilus methylotrophus AS1 expressing a mutant form of dapA (dapA24) encoding a dihydrodipicolinate synthase desensitized from feedback inhibition by L-lysine could secrete L-lysine into the medium, but also maintained a high concentration of intracellular L-lysine. To improve the yield from excretion, we attempted to introduce an L-lysine/L-arginine exporter (LysE) from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Transport Systems, Basic
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bioreactors

Share to Lysine

Share to Methanol

Share to Molecular Sequence Data

Share to Mutation

Share to Transformation, Bacterial

Source

Identifiers

PMID: 16870294
DOI: 10.1016/j.jbiotec.2006.06.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of L-lysine production in methylotroph Methylophilus methylotrophus by introducing a mutant LysE exporter.PMID 16870294Read ↗

Disruption of metF increased L-lysine production by Methylophilus methylotrophus from methanol.Semantic proximity Read ↗

Improving lysine production by Corynebacterium glutamicum through DNA microarray-based identification of novel target genes.Semantic proximity Read ↗

Analysis and manipulation of aspartate pathway genes for L-lysine overproduction from methanol by Bacillus methanolicus.Semantic proximity Read ↗

Site-directed mutagenesis and feedback-resistant N-acetyl-L-glutamate kinase (NAGK) increase Corynebacterium crenatum L-arginine production.Semantic proximity Read ↗

Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.Semantic proximity Read ↗

A leuC mutation leading to increased L-lysine production and rel-independent global expression changes in Corynebacterium glutamicum.Semantic proximity Read ↗

Improved L-ornithine production in Corynebacterium crenatum by introducing an artificial linear transacetylation pathway.Semantic proximity Read ↗

Construction of Lactobacillus plantarum strain with enhanced L-lysine yield.Semantic proximity Read ↗

Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50 degrees C.Semantic proximity Read ↗

Overproduction of L-Lysine from methanol by Methylobacillus glycogenes derivatives carrying a plasmid with a mutated dapA gene.Semantic proximity Read ↗

Pyruvate kinase deletion as an effective phenotype to enhance lysine production in Corynebacterium glutamicum ATCC13032: Redirecting the carbon flow to a precursor metabolite.Semantic proximity Read ↗

Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.