Article
Construction of Lactobacillus plantarum strain with enhanced L-lysine yield.
Journal of applied microbiology - 1 Mar 2007
Cahyanto M N, Kawasaki H, Nagashio M, Fujiyama K, Seki T
Abstract excerpt
AIM: To enhance L-lysine secretion in Lactobacillus plantarum. METHODS AND RESULTS: An S-2-aminoethyl-L-cystein (AEC)-resistant mutant of L. plantarum was isolated, and it produced L-lysine at considerably higher level than the parent strain. Aspartokinase in the mutant has been desensitized to feedback inhibition by L-lysine. The nucleotide sequence analysis of thrA2 that codes for aspartokinase in the mutant...
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