Article
Improving lysine production by Corynebacterium glutamicum through DNA microarray-based identification of novel target genes.
Applied microbiology and biotechnology - 1 Sept 2007
Sindelar Georg, Wendisch Volker F
Abstract excerpt
For the biotechnological production of L: -lysine, mainly strains of Corynebacterium glutamicum are used, which have been obtained by classical mutagenesis and screening or selection or by metabolic engineering. Gene targets for the amplification and deregulation of the lysine biosynthesis pathway, for the improvement of carbon precursor supply and of nicotinamide adenine dinucleotide phosphate (reduced form)...
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