Article
Analysis of coding variants in the betacellulin gene in type 2 diabetes and insulin secretion in African American subjects.
BMC medical genetics - 25 Jul 2006
Elbein Steven C, Wang Xiaoqin, Karim Mohammad A, Chu Winston S, Silver Kristi D
Abstract excerpt
BACKGROUND: Betacellulin is a member of the epidermal growth factor family, expressed at the highest levels predominantly in the pancreas and thought to be involved in islet neogenesis and regeneration. Nonsynonymous coding variants were reported to be associated with type 2 diabetes in African American subjects. We tested the hypotheses that these previously identified variants were associated with type 2...
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