Article
The exon 1 Cys7Gly polymorphism within the betacellulin gene is associated with type 2 diabetes in African Americans.
Diabetes - 1 Apr 2005
Silver Kristi, Tolea Magdalena, Wang Jian, Pollin Toni I, Yao Flora, Mitchell Braxton D
Abstract excerpt
In vitro and in vivo studies suggest a role for betacellulin in islet neogenesis and regeneration. Since abnormalities in beta-cell function play a role in the development of type 2 diabetes, a mutation in the betacellulin gene could potentially contribute to the development of type 2 diabetes. Using RT-PCR, we initially determined that betacellulin was expressed in 9- to 24-week-old human fetal pancreas. We then...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.