Article
MTHFR C677T polymorphism is not associated with placental abruption or preeclampsia in Finnish women.
Hypertension in pregnancy - 1 Jan 2006
Jääskeläinen Ester, Keski-Nisula Leea, Toivonen Sari, Romppanen Eeva-Liisa, Helisalmi Seppo, Punnonen Kari, Heinonen Seppo
Abstract excerpt
OBJECTIVE: The aim of our study was to examine genetic variability in the gene encoding methylenetetrahydrofolate reductase (MTHFR) and individual susceptibility to the placental abruption or preeclampsia. METHODS: 362 women (133 with preeclampsia, 117 with placental abruption, and 112 healthy controls) were genotyped for C677T polymorphism in the MTHFR gene. RESULTS: Similar genotype distributions were observed...
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