Article
Plasminogen activator inhibitor-1 polymorphism in women with pre-eclampsia.
Genetic testing - 1 Jan 2003
Häkli Tanja, Romppanen Eeva-Liisa, Hiltunen Mikko, Helisalmi Seppo, Punnonen Kari, Heinonen Seppo
Abstract excerpt
We determined whether or not genetic variability in the promoter region of the gene encoding plasminogen activator inhibitor-1 (PAI1) contributes to individual differences in susceptibility to the development of preeclampsia. The study involved 133 preeclamptic and 115 healthy control pregnant women who were genotyped for a single-nucleotide insertion/deletion polymorphism (4G/5G) at position -675 in the PAI1...
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