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Article

The methylenetetrahydrofolate reductase 677 C-->T polymorphism and preeclampsia in two populations.

Obstetrics and gynecology - 1 Jun 2002

Prasmusinto D, Skrablin S, Hofstaetter C, Fimmers R, van der Ven K

Abstract excerpt

OBJECTIVE: The C677T polymorphism of the 5,10 methylenetetrahydrofolate reductase (MTHFR) gene is associated with decreased MTHFR activity and elevated plasma homocysteine levels with the result of an increased risk for vascular disease. Because thrombosis of the maternal spiral arteries can be one of the causative events in the disease, it has been suggested that the C677T polymorphism may also play a role in...

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Source

Identifiers

PMID: 12052604
DOI: 10.1016/s0029-7844(02)01997-x

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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