Article
Tumour necrosis factor gene complex polymorphisms in chronic obstructive pulmonary disease.
Respiratory medicine - 1 Feb 2007
Ruse Charlotte E, Hill Maureen C, Tobin Martin, Neale Natalie, Connolly Martin J, Parker Stuart G, Wardlaw Andrew J
Abstract excerpt
We aimed to examine the role of tumour necrosis factor gene complex polymorphisms in subjects with chronic obstructive pulmonary disease (COPD). We hypothesized that individuals possessing polymorphic variants associated with higher tumour necrosis factor (TNF) secretion would be more susceptible to and/or have more severe disease. Patients with COPD and population controls underwent detailed clinical...
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