Article
Gene–gene interactions of IL13 and IL4RA variants in immediate allergic reactions to betalactam antibiotics
1 Oct 2006
Abstract excerpt
OBJECTIVES: Immediate reactions - particularly anaphylactic ones - to betalactams are the most common adverse reactions to antibiotics mediated by a specific immunologic mechanism. The genetic risk factors influencing these mechanisms are poorly known. We aimed to evaluate the association between immediate allergic reactions to betalactams and the polymorphisms of IL13 (R130Q and -1055C>T variants) and IL4RA...
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