Article
Polymorphisms and haplotype analysis of IL-4Ralpha Q576R and I75V in patients with penicillin allergy.
European journal of clinical pharmacology - 1 Sept 2009
Huang Chen-Zheng, Yang Jing, Qiao Hai-Ling, Jia Lin-Jing
Abstract excerpt
BACKGROUND: The interleukin (IL)-4 and IL-4R genes are linked to allergic diseases and atopy and elevated serum IgE levels closely follow the presentation of penicillin allergy. We have evaluated the association between specific immunoglobulin (Ig)E, polymorphisms of IL-4Ralpha, and penicillin allergy. METHODS: Eight types of specific IgE to penicillins were detected with the radioallergosorbent test (RAST) in...
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