Article
Interaction of endothelin with renal nerves modulates kidney function in spontaneously hypertensive rats.
Kidney & blood pressure research - 1 Jan 2006
Girchev Radoslav A, Bäcker Angela, Markova Petia P, Kramer Herbert J
Abstract excerpt
BACKGROUND AND METHODS: We investigated kidney function, renal endothelin-1 concentration, prepro-endothelin-1 mRNA as well as endothelin receptor A and B mRNA expression and receptor properties in normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) with intact renal nerves and 7 days after renal denervation. In addition, responses of renal function to the non-selective ETA/ETB receptor...
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