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Article

Renomedullary Interstitial Cell Endothelin A Receptors Regulate BP and Renal Function.

Journal of the American Society of Nephrology : JASN - 1 Jul 2020

Hu Chunyan, Lakshmipathi Jayalakshmi, Stuart Deborah, Peti-Peterdi Janos, Gyarmati Georgina, Hao Chuan-Ming, Hansell Peter, Kohan Donald E

Abstract excerpt

BACKGROUND: The physiologic role of renomedullary interstitial cells, which are uniquely and abundantly found in the renal inner medulla, is largely unknown. Endothelin A receptors regulate multiple aspects of renomedullary interstitial cell function in vitro. METHODS: To assess the effect of targeting renomedullary interstitial cell endothelin A receptors in vivo, we generated a mouse knockout model with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32487560
DOI: 10.1681/ASN.2020020232
PMCID: PMC7351004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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