Article
Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics.
American journal of physiology. Heart and circulatory physiology - 1 Jan 2001
Audoly L P, Ruan X, Wagner V A, Goulet J L, Tilley S L, Koller B H, Coffman T M, Arendshorst W J
Abstract excerpt
The kidney plays a central role in long-term regulation of arterial blood pressure and salt and water homeostasis. This is achieved in part by the local actions of paracrine and autacoid mediators such as the arachidonic acid-prostanoid system. The present study tested the role of specific PGE(2) E-prostanoid (EP) receptors in the regulation of renal hemodynamics and vascular reactivity to PGE(2). Specifically,...
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