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Article

Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain.

Infection and immunity - 1 Aug 2006

Pechous Roger, Celli Jean, Penoske Renee, Hayes Stanley F, Frank Dara W, Zahrt Thomas C

Abstract excerpt

Francisella tularensis is a facultative intracellular pathogen and is the etiological agent of tularemia. It is capable of escaping from the phagosome, replicating to high numbers in the cytosol, and inducing apoptosis in macrophages of a variety of hosts. F. tularensis has received significant attention recently due to its potential use as a bioweapon. Currently, there is no licensed vaccine against F....

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Identifiers

PMID: 16861631
DOI: 10.1128/IAI.00666-06
PMCID: PMC1539594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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