Article
Complex memory T-cell phenotypes revealed by coexpression of CD62L and CCR7.
Journal of virology - 1 Apr 2005
Unsoeld Heike, Pircher Hanspeter
Abstract excerpt
Antigen-experienced T cells have been divided into CD62L+ CCR7+ central memory (TCM) and CD62L- CCR7- effector memory (TEM) cells. Here, we examined coexpression of CD62L and CCR7 in lymphocytic choriomeningitis virus-specific memory CD8 T cells from both lymphoid and nonlymphoid tissues. Three main points emerged: firstly, memory cells frequently expressed a mixed CD62L- CCR7+ phenotype that differed from the...
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