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Article

Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway.

Journal of molecular and cellular cardiology - 1 Sept 2006

Pellieux Corinne, Aasum Ellen, Larsen Terje S, Montessuit Christophe, Papageorgiou Irène, Pedrazzini Thierry, Lerch René

Abstract excerpt

Heart failure is associated with downregulation of the fatty acid oxidation pathway in the ventricular myocardium. Since angiotensin II plays a critical role in myocardial phenotypic changes associated with heart failure, we investigated the effect of chronic angiotensin II stimulation on the fatty acid oxidation pathway in transgenic (TG) mice with targeted overexpression of angiotensinogen in the myocardium...

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Identifiers

PMID: 16859699
DOI: 10.1016/j.yjmcc.2006.06.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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